Gluconolactone is a polyhydroxy acid (PHA) known for its gentle exfoliating and hydrating properties. It delivers results similar to AHAs like glycolic acid, but with far less irritation, making it a great choice for sensitive, dry, mature, or compromised skin.
It’s a water-soluble powder derived from glucose and is commonly used in skincare formulations under the INCI name Gluconolactone (also known as Glucono-delta-lactone).
Benefits.
Gentle Exfoliation
Helps lift away dead skin cells on the surface, revealing smoother, brighter skin without harsh tingling or redness.
Deep Hydration.
Acts as a humectant, drawing moisture into the skin to keep it soft, plump, and comfortable.
Barrier Support.
Strengthens the skin’s natural barrier and improves overall texture with continued use.
Antioxidant & Anti-Aging Care.
Helps protect against environmental stress while reducing the appearance of fine lines and early signs of aging.
Chelating & pH Support.
Improves formula stability by binding metal ions and assisting with pH balance.
–Usage Rates
Usage depends on the product type and intended performance:
0.1–5% – Daily leave-on products like serums and creams.
5–15% – Exfoliating treatments and masks (occasionally up to 20%).
Up to 0.075% – Eye-area and very delicate formulations.
Up to 15% – Maximum commonly reported cosmetic use.
Lower levels (1–5%) are ideal for daily hydration and gentle exfoliation, especially for sensitive skin. Higher levels (10–15%) are best suited for rinse-off or targeted exfoliating products and should be carefully balanced for comfort and pH.
Gluconolactone is widely used in:
Toners and essences
Serums and moisturizers
Gentle exfoliating masks
Post-treatment skincare
Sensitive-skin formulas
Cleansers and body care products
Ideal pH: Approximately 3.4–5.5
