Isobutylamido Thiazolyl Resorcinol (Thiamidol)

Isobutylamido Thiazolyl Resorcinol

Isobutylamido Thiazolyl Resorcinol is a high-performance skin-brightening active known for its selective tyrosinase inhibition, helping to visibly reduce post-inflammatory hyperpigmentation such as acne marks, dark spots, melasma, and sun-induced discoloration.

Clinical studies show visible improvement within weeks, with optimal results seen after 12 weeks of consistent use. It delivers effective brightening comparable to hydroquinone, with excellent skin tolerance, including on darker skin tones (Fitzpatrick V–VI).

Key Benefits

Targets post-inflammatory pigmentation

Helps fade acne marks and dark spots

Supports a more even skin tone

Helps prevent UV-induced darkening

Suitable for a wide range of skin tones

Well tolerated at recommended use levels

Recommended Use

Use day and night; may be applied up to 3 times daily

Best results when combined with other brightening actives

Ideal for spot treatments and overall tone correction

INCI: Isobutylamido Thiazolyl Resorcinol

Use Level: 0.1–0.5%

0.2–0.5% for general brightening

0.5% for targeted spot treatments

Solubility: Glycols

pH Stability: 4.0–5.5

Heat Sensitivity: Avoid prolonged heating above 80°C

Appearance: Light-colored powder

—

Applications

Serums, creams, lotions, masks, peels, and post-procedure treatments.